Not the least of these is the travel time involved. Space is so large, and human technology so limited, that the time it would take to travel to another star presents a significant barrier.to reach Proxima Centauri, the nearest star to the Sun, at its current speed.
One potential solution would be generation ships, which would see multiple generations of space travelers live and die before reaching the final destination. Another would be artificial hibernation, if it could be successfully implemented. "Here, we show that activating a subpopulation of preoptic area neurons by a chemogenetic strategy reliably induces hypothermia in anesthetized and freely moving macaques,""Altogether, our findings demonstrate the central regulation of body temperature in primates and pave the way for future application in clinical practice."